A Paper-based Molecular Calcium Sensor Using Gold Nanoparticles
The goal of this project is to develop a paper-based microfluidic sensor for calcium using immobilized gold nanoparticles. This work builds off of previously developed lab expertise in paper microfluidic device fabrication and gold nanoparticle mediated calcium sensing. The primary outcome for this project is the development of a platform capable of detecting calcium above specified thresholds from liquid samples at Technology Readiness Level 4. It will develop the scientific infrastructure of Louisiana and the United States by training two undergraduate biomedical engineering students in microfluidic principles. These students will also participate in an entrepreneurship competition on campus and engage with the general public to develop skills necessary for successful transition from school into the STEM workforce. This project will be completed in twelve months. The PI will focus significant efforts on student engagement, with particular attention to underrepresented groups within STEM to increase diversity. The overall project is in alignment with NASA mission goals, particularly the goals of the Human Exploration and Operations Mission Directorate. The development of this technology will have applications outside space missions as well, including agriculture, biosensing, and biomedical diagnostics.
Principal Investigator: Hollins, Bryant -- Biomedical Engineering
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