Material Performance of Environmentally Responsive Micro- and Nanoscale Polymeric Biomaterials
Understanding the in vitro performance of responsive nanoscale biomaterials remains as an unmet need within the field of polymer science and controlled drug release and, therefore, will significantly impact the field. The objective of this proposal is to evaluate the effects size and surface area plays on the in vitro behavior of environmentally responsive micro- and nanoscale hydrogels. To accomplish this, a series of micro- and nanopatterned, environmentally responsive, hydrogel nanofeatures and nanoparticles will be developed. Along with experimental studies, a theoretical model will be developed to serve as a means of predicting nanoscale swelling and subsequent drug release behavior.
Principal Investigator: Moore, Mary Caldorera -- Biomedical Engineering, Engineering and Technology Management, CBERS, Molecular Science and Nanotechnology
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