Welcome
Areas of Research
Office of the Vice President
Office of Intellectual Property & Commercialization
Office of Sponsored Projects
Compliance & Review Boards
Research Foundation
Facilities
Forms & Downloads
Funding Opportunities
Policies & Procedures
Proposal Preparation
Resource Links
Routing Proposals
Training & Workshops
Travel FAQs
News Articles
Spotlight Articles
Breeze Newsletter
Events Calendar
Browse Projects
Browse People

Cardiomyocyte Generation for Cardiac Muscle Repair

Description :  

Prolonged exposure to low-gravity environments poses a serious health risk to astronauts. One negative physical consequence is the weakening of cardiac muscle resulting from a decrease in the workload required to pump blood through the circulatory system. In light of limited cardiac tissue regeneration capacity, this project may explore repair methods that do not require a total heart transplant. The objective of the researchers of this project is to grow cardiomyocytes on a biocompatible substrate that may be used as an implant to restore damaged cardiac tissue. The investigators will utilize murine embryonic stem cells (mESCs) as a preliminary model for human cells. It is proposed that optimization of cell culture conditions may increase successful cardiomyocyte generation. The investigators will then extract RNA to determine genetic expression profiles and verify differentiation. The results of this project may, therefore, benefit the health of astronauts and NASA’s long term goal of space colony establishment.


Principal Investigator:  Newman, Jamie  --  Biological Sciences
Collaborators:  
Funding Agencies:  NASA/LaSPACE/LSU
Amount Awarded:  5,000

Start Period:  08/08/2014 End Period:  04/08/2015
Related People

October 21st, 2017

Browse Projects

Browse People

Recent Articles

2017 Annual Student Research Symposium...

More News...

Page Tools

Print Page      Email Page

Louisiana Tech University, A Member of the University of Louisiana System
2017 Louisiana Tech University P.O. Box 3178 Ruston, LA 71272