Development of a Highly Reliable Boron-Doped Ultrananocrystalline Diamond Microsensor for Chronic Monitoring of Neurochemicals
In response to limitations observed in carbon-fiber microelectrodes utilized in assessing brain activity concerning abnormal neurochemical signaling, the objective of the investigator of this research is to develop a boron-doped ultrananocrystalline diamond microsensor for sustained and continuous neurochemical recording. This may be accomplished through: the development of a fundamental understanding of electrode property changes in biofluids, and engineering new strategies for surface fouling mitigation. These steps may utilize microdisk and microwire electrode geometries and techniques including Flow Injection Analysis, Cyclic Voltammetry, and Impedance Spectroscopy. In meeting these objectives, the investigator aims to advance neurochemical monitoring capabilities, which can apply to individuals with schizophrenia, Parkinson`s Disease, traumatic brain injury, and drug addiction.
Principal Investigator: Arumugam, Prabhu -- Mechanical Engineering, Institute for Micromanufacturing, Molecular Science and Nanotechnology
|Start Period: 07/01/2014
||End Period: 07/30/2017