Development of Carbon Nanotube Based Multifunctional Electrochemical Probes for Single Cell Analysis
The objective of the investigators of this research is to develop Carbon Nanotube (CNT)-Metal Concentric Electrochemical nanoProbes (CNT-M CEnP) that would allow both sensing and studying capabilities for biological processes in single cells. Ultimately, the investigators aim to micro fabricate a probe that contains an array of up to five concentric nanoelectrodes (cNEs), possibly allowing for the analysis of multiple analytes within a live cell in real time. These goals may be met through: the utilization of vertically aligned carbon nanotubes (VACNFs) as disk nanoelectrodes, designing and fabricating a CNT-platinum concentric nanoprobe, characterizing the nanoprobe for signal reproducibility, and demonstrating the advantages of the probe in a measurement of dopamine in the presence of ascorbic acid. Nanoprobes and their applications in studying subcellular processes may enhance indicating disease onset and novel health monitoring devices.
Principal Investigator: Arumugam, Prabhu -- Mechanical Engineering, Institute for Micromanufacturing, Molecular Science and Nanotechnology
|Start Period: 06/01/2014
||End Period: 05/31/2015
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