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Genetic Assessment of the Space Environment Using MEMS Technology

Description :  

In response to NASA`s Human Exploration and Operations Mission Directorate (HEOMD) associated with the Mars Science Laboratory Mission, the investigators of this research seek to advance biodosimetric techniques necessary for monitoring radiation exposure. Specifically, the investigators` objective is to develop an automated system functioning as a hodoscope-informed, quantitative reverse transcription polymerase chain reaction with melting curve analysis (HI qRT- PCR/MCA). This system is expected to analyze radiation effects on biological samples in real time through pinpoint mRNA extraction, reverse transcription, PCR replication and melting curve analysis. Data collected from this system could provide insight on the mechanisms of gene expression in samples exposed to radiation, which may improve radiation risk analysis in space missions.  

Principal Investigator:  Crews, Niel  --  Institute for Micromanufacturing
Collaborators:  Wilson, C. and Derosa, P.
Funding Agencies:  BoR
Amount Awarded:  750,000

Start Period:  09/01/2013 End Period:  08/31/2016
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November 15th, 2018

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