Description :  This project applies nanochemistry to the development of new microcapsules for sustained drug delivery. The fundamental characteristics of the layer-by-layer self-assembly of nanoorganized shells performed by alternate electrostatic adsorption of oppositely charged polyelectrolytes are the subjects of this study. These microshells will be loaded with drugs or enzymes, and the researcher will investigate the medical and biological activity of the encapsulated compounds and their controlled release. The concept of “bio/nanoreactors” based on enzyme encasing in nanoorganized shells will be introduced. The researcher hopes that project results will increase drug therapeutic availability both for oral administration and for injection formulations.

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Principal Investigator:  Lvov, Yuri  --  Chemistry

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Collaborators:  

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Funding Agencies:  Board of Regents

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Amount Awarded:  $129,586

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Start Period:  06/01/2002

End Period:  06/03/2005