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Correction of Mutations Using Tailor-made Recombinases
Description : The goal of this research is to develop efficient genome manipulation approach based on tailor-made site-specific recombinases. The approach will be based on the ability of site-specific recombinases to replace DNA fragments provided these fragments are flanked by the recombination targets for these recombinases. By replacing defective DNA with mutation-free DNA, we can correct a mutation that causes sickle cell disease in cultured human cells SC-1.
Principal Investigator: Voziyanov, Yuri -- Biological Sciences
Collaborators:
Funding Agencies: NSF/BoR Pfund
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End Period: 00/00/0000 |
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Louisiana Tech University, A Member of the University of Louisiana System
© 2009 Louisiana Tech University P.O. Box 3178 Ruston, LA 71272
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November 21st, 2009
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